abstract：:Oxidized lipoprotein(a) (oxLp(a)) is a more potent marker of atherogenesis than native Lp(a). However, the molecular mechanisms of oxLp(a) activity are not clear. Reactive oxygen species (ROS) have recently been suggested as acting as intracellular second messengers. In this study, the effects of oxLp(a) on endothelia...

journal_title：Lipids

authors： Wei DH,Zhang XL,Wang R,Zeng JF,Zhang K,Yang J,Li S,Lin XL,Jiang ZS,Wang GX,Wang Z

更新日期：2013-06-01 00:00:00

abstract：:Stearoyl-coenzyme A desaturase-1 (SCD1) is a rate-limiting enzyme that catalyzes the biosynthesis of monounsaturated fatty acids from saturated fatty acids. Recently, SCD1 down-regulation has been implicated in the prevention of obesity, and the improvement of insulin and leptin sensitivity. In this study, we examined...

journal_title：Lipids

authors： Beppu F,Hosokawa M,Yim MJ,Shinoda T,Miyashita K

更新日期：2013-05-01 00:00:00

abstract：:Plasma lipidomic studies using high performance liquid chromatography and mass spectroscopy offer detailed insights into metabolic processes. Taking the example of the most abundant plasma lipid class (phosphatidylcholines) we used the rich phenotypic and lipidomic data from the ongoing San Antonio Family Heart Study ...

journal_title：Lipids

authors： Kulkarni H,Meikle PJ,Mamtani M,Weir JM,Barlow CK,Jowett JB,Bellis C,Dyer TD,Johnson MP,Rainwater DL,Almasy L,Mahaney MC,Comuzzie AG,Blangero J,Curran JE

更新日期：2013-05-01 00:00:00

abstract：:Membrane phospholipid (PL) composition has been shown to affect cellular function by altering membrane physical structure. The sarcolemma plasma membrane (SLpm) is integral to skeletal muscle function and health. Previous studies assessing SLpm PL composition have demonstrated contamination from transverse (t)-tubule,...

journal_title：Lipids

authors： Fajardo VA,McMeekin L,Basic A,Lamb GD,Murphy RM,LeBlanc PJ

更新日期：2013-04-01 00:00:00

abstract：:Lysophosphatidic acid (lysoPtdOH), a lysophospholipid mediator, exerts diverse physiological effects, including angiogenesis, through its specific G-protein-coupled receptors. Previously, we showed that unfertilized hen egg white contains polyunsaturated fatty acid-rich lysoPtdOH and lysophospholipase D (lysoPLD). Her...

journal_title：Lipids

authors： Morishige J,Uto Y,Hori H,Satouchi K,Yoshiomoto T,Tokumura A

更新日期：2013-03-01 00:00:00

abstract：:High-performance liquid chromatography-electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS) approaches have enabled high selectivity and sensitivity for the identification and quantification of glucosylceramide molecular species. Here we demonstrate that HPLC-ESI-MS/MS is an efficient method for character...

journal_title：Lipids

authors： Imai H,Hattori H,Watanabe M

更新日期：2012-12-01 00:00:00

abstract：:This study investigated the effect of triticale dried distillers' grain with solubles (DDGS), flax (FS) and sunflower (SS) seed on growth and the fatty acid profile of subcutaneous (SQ) fat in individually housed steers (n = 15 per diet) fed ad libitum (DM basis); (1) control (CON) 90% barley grain + 10% barley silage...

journal_title：Lipids

authors： He ML,Sultana H,Oba M,Kastelic JP,Dugan ME,McKinnon JJ,McAllister TA

更新日期：2012-12-01 00:00:00

abstract：:The weight loss supplement conjugated linoleic acid (CLA) consists of an equal mixture of trans-10,cis-12 (10,12) and cis-9,trans-11 (9,11) isomers. However, high levels of mixed CLA isomers, or the 10,12 isomer, causes chronic inflammation, lipodystrophy, or insulin resistance. We previously demonstrated that 10,12 C...

journal_title：Lipids

authors： Reardon M,Gobern S,Martinez K,Shen W,Reid T,McIntosh M

更新日期：2012-11-01 00:00:00

abstract：:The present study enumerates the synthesis, spectroscopic characterization, and evaluation of anticancer potential of esters of two n-9 fatty acids viz., oleic acid (OLA) and ricinoleic acid (RCA) with 2,4- or 2,6-diisopropylphenol. The synthesis strategy involved esterification of the hydroxyl group of diisopropylphe...

journal_title：Lipids

authors： Khan AA,Husain A,Jabeen M,Mustafa J,Owais M

更新日期：2012-10-01 00:00:00

abstract：:Red blood cell (RBC) fatty acid (FA) patterns have been shown to predict risk for cardiovascular and other chronic diseases. As part of a project analyzing RBC samples from the Women's Health Initiative Memory Study (WHIMS) we observed implausibly low levels of highly unsaturated fatty acids (HUFA) suggestive of degra...

journal_title：Lipids

authors： Pottala JV,Espeland MA,Polreis J,Robinson J,Harris WS

更新日期：2012-09-01 00:00:00

abstract：:This study examined the effects of sesamin inclusion in vegetable oil-based diets fed to Atlantic salmon (Salmo salar L.). The diets used differed in n-6/n-3 fatty acid (FA) ratio (0.5 and 1) and sesamin content (high 5.8 g/kg, low 1.16 g/kg and no sesamin). The oils used in the feeds were a mixture of rapeseed, linse...

journal_title：Lipids

authors： Schiller Vestergren A,Wagner L,Pickova J,Rosenlund G,Kamal-Eldin A,Trattner S

更新日期：2012-09-01 00:00:00

abstract：:The particular interest in supplementing human foods with n-3 fatty acids has arisen from the findings that this series of polyunsaturated fatty acids (PUFA) have an impact on neuronal functions. Indeed vertebrates, including humans, preferentially use docosahexaenoic acid (DHA, 22:6n-3) over other long-chain n-3 PUFA...

journal_title：Lipids

authors： Pifferi F,Perret M,Guesnet P,Aujard F,Alessandri JM

更新日期：2012-08-01 00:00:00

abstract：:(8R)-Hydroperoxy-(9Z,12Z)-octadecadienoic acid (8-HPODE) is formed by aspergilli as an intermediate in biosynthesis of oxylipins with effects on sporulation. 8-HPODE is transformed by separate diol synthases to (5S,8R)-dihydroxy- and (8R,11S)-dihydroxy-(9Z,12Z)-octadecadienoic acids (5,8- and 8,11-DiHODE). The former ...

journal_title：Lipids

authors： Jernerén F,Oliw EH

更新日期：2012-07-01 00:00:00

abstract：:When fatty acids in fish are analyzed, results in percentage form (profile analysis) are mostly reported. However, the much more useful results expressed as mg/100 g (absolute analysis) is the main information required. Absolute methods based on calibration curves are of good accuracy but with a high degree of complex...

journal_title：Lipids

authors： Nevigato T,Masci M,Orban E,Di Lena G,Casini I,Caproni R

更新日期：2012-07-01 00:00:00

abstract：:The proximate and fatty acid compositions of the commercially important fish species (Engraulis encrasicolus, Alosa alosa, Belone belone, Scorpaena porcus, Pomatomus saltatrix, Mullus barbatus) from the Sinop region of the Black Sea were examined. The fat contents ranged from 1.26% (for scorpion fish) to 18.12% (for s...

journal_title：Lipids

authors： Kocatepe D,Turan H

更新日期：2012-06-01 00:00:00

abstract：:Camelina sativa is an oilseed plant rich in n-3 and n-6 fatty acids and extruding the seeds results in high protein meal (*40%) containing high levels of n-3 fatty acids. In this study, we examined the effects of feeding extruded defatted camelina meal to commercial laying hens, measuring egg production, quality, and ...

journal_title：Lipids

authors： Kakani R,Fowler J,Haq AU,Murphy EJ,Rosenberger TA,Berhow M,Bailey CA

更新日期：2012-05-01 00:00:00

abstract：:Paraoxonase 1 (PON 1) has antioxidant and cardioprotective properties and is abnormally low in type 2 diabetic serum. This study aimed to determine the effect of type 2 diabetes and meals rich in saturated fat and oleic acid on PON1 activity in chylomicrons and very low density lipoproteins (VLDL). PON1 arylesterase a...

journal_title：Lipids

authors： Manning PJ,Jong SA,Ryalls AR,Sutherland WH

更新日期：2012-03-01 00:00:00

abstract：:Commercial fish oils and foods containing fish may contain trans and/or isomerized fatty acids (FA) produced during processing or as part of prepared foods. The current American Oil Chemists' Society (AOCS) official method for marine oils (method Ce 1i-07) is based on separation by use of poly(ethylene glycol) (PEG) c...

journal_title：Lipids

authors： Santercole V,Delmonte P,Kramer JK

更新日期：2012-03-01 00:00:00

abstract：:A sucrose-rich diet (SRD) induces insulin resistance and dyslipidemia with impaired hepatic glucose production and gluconeogenesis, accompanied by altered post-receptor insulin signaling steps. The aim of this study was to examine the effectiveness of fish oil (FO) to reverse or improve the impaired hepatic glucose me...

journal_title：Lipids

authors： Hein GJ,Chicco A,Lombardo YB

更新日期：2012-02-01 00:00:00

abstract：:Jasmonic acid (JA) is synthesized from linolenic acid (18:3n-3) by sequential action of 13-lipoxygenase, allene oxide synthase (AOS), and allene oxide cyclase. The fungus Lasiodiplodia theobromae can produce large amounts of JA and was recently reported to form the JA precursor 12-oxophytodienoic acid. The objective o...

journal_title：Lipids

authors： Jernerén F,Eng F,Hamberg M,Oliw EH

更新日期：2012-01-01 00:00:00

abstract：:Policosanol is a poorly absorbed nutritional supplement used primarily for cholesterol management. Findings from previous trials evaluating the effects of policosanol are mixed with early data reporting positive lipid effects while more recent studies indicate negligible efficacy. We hypothesized that re-formulating p...

journal_title：Lipids

authors： Backes JM,Gibson CA,Ruisinger JF,Moriarty PM

更新日期：2011-10-01 00:00:00

abstract：:Tissue and blood fatty acid compositions are used as biological markers of fatty acid intakes to improve dietary assessments. These approaches are invasive and not well accepted, particularly in infants and young children. We developed a sensitive method for the analysis of fatty acids in cheek cell glycerophospholipi...

journal_title：Lipids

authors： Klingler M,Demmelmair H,Koletzko B,Glaser C

更新日期：2011-10-01 00:00:00

abstract：:Type 2 diabetes and dyslipidemia are risk factors for cardiovascular disease. However, mechanisms by which hypertriglyceridemia influences atherogenesis remain unclear. We examined effects of dyslipidemic diabetic serum on macrophage lipid accumulation as a model of foam cell formation. Normal human macrophages were c...

journal_title：Lipids

authors： Wong BX,Kyle RA,Myhill PC,Croft KD,Quinn CM,Jessup W,Yeap BB

更新日期：2011-10-01 00:00:00

abstract：:Diacylglycerol acyltransferase (DGAT) catalyzes the final step of triacylglycerol (TAG) synthesis, and is considered as a potential target to control hypertriglyceridemia or other metabolic disorders. In this study, we found that the extract of rose petals suppressed TAG synthesis in cultured cells, and that the extra...

journal_title：Lipids

authors： Kondo H,Hashizume K,Shibuya Y,Hase T,Murase T

更新日期：2011-08-01 00:00:00

abstract：:Guar gum has a well-recognized hypolipidemic effect. This effect is thought to be due to the physicochemical properties of guar gum, which may cause changes in adsorption of lipids or the viscosity of the intestinal contents. Guar gum is a non-specific absorption inhibitor of any type of lipid-soluble compound. Perman...

journal_title：Lipids

authors： Shirouchi B,Kawamura S,Matsuoka R,Baba S,Nagata K,Shiratake S,Tomoyori H,Imaizumi K,Sato M

更新日期：2011-08-01 00:00:00

abstract：:Oxidative stress is thought to play an important role in atherogenesis. The statin group of cholesterol-lowering drugs have been shown to reduce cardiovascular events and possess antioxidant properties. We aimed to assess the effects of simvastatin on a novel measure of prooxidant-antioxidant balance (PAB) in dyslipid...

journal_title：Lipids

authors： Parizadeh SM,Azarpazhooh MR,Moohebati M,Nematy M,Ghayour-Mobarhan M,Tavallaie S,Rahsepar AA,Amini M,Sahebkar A,Mohammadi M,Ferns GA

更新日期：2011-04-01 00:00:00

abstract：:9-Hydroxy-2E-decenoic acid (9-HDA) is a precursor of the queen-produced substance, 9-oxo-2E-decenoic acid (9-ODA), which has various important functions and roles for caste maintenance in honeybee colonies (Apis mellifera). 9-HDA in royal jelly is considered to be a metabolite of 9-ODA produced by worker bees, and it ...

journal_title：Lipids

authors： Kodai T,Nakatani T,Noda N

更新日期：2011-03-01 00:00:00

abstract：:Over 50 years of research has sought to define the role dietary fat plays in cardiovascular disease (CVD) risk. Although optimal dietary fat quantity has been keenly pursued over past decades, attention has recently centered on the value of dietary fat quality. The purpose of the present review is to provide a critica...

journal_title：Lipids

authors： Gillingham LG,Harris-Janz S,Jones PJ

更新日期：2011-03-01 00:00:00

abstract：:Serum opacity factor (SOF) is a streptococcal protein that disrupts the structure of human high density lipoproteins (HDL) releasing lipid-free apo A-I while forming a large cholesteryl ester-rich particle and a small neo HDL. Given its low cholesterol and high phospholipid contents, we tested the hypotheses that neo ...

journal_title：Lipids

authors： Tchoua U,Rosales C,Tang D,Gillard BK,Vaughan A,Lin HY,Courtney HS,Pownall HJ

更新日期：2010-12-01 00:00:00

abstract：:Electron paramagnetic resonance (EPR) in conjunction with a slow-tumbling simulation was utilized for defining stratum corneum (SC) lipid structure. SC from the back of hairless mouse (HOS:HR-1) was stripped consecutively from one to three or four times using a glass plate coated with a cyanoacrylate resin. Aliphatic ...

journal_title：Lipids

authors： Nakagawa K,Anzai K

更新日期：2010-11-01 00:00:00

abstract：:Dysregulation of lipid metabolism is frequently associated with inflammatory conditions. The mechanism of this association is still not clearly defined. Recently, we identified a nuclear oxysterol, 25-hydroxycholesterol-3-sulfate (25HC3S), as an important regulatory molecule involved in lipid metabolism in hepatocytes...

journal_title：Lipids

authors： Xu L,Bai Q,Rodriguez-Agudo D,Hylemon PB,Heuman DM,Pandak WM,Ren S

更新日期：2010-09-01 00:00:00

abstract：:Sphingomyelin was isolated from cysts of the brine shrimp Artemia franciscana using QAE-Sephadex A25, Florisil and Iatrobeads column chromatographies. The chemical structure was identified using thin-layer chromatography, gas-liquid chromatography, infrared spectroscopy and matrix-assisted laser desorption ionization ...

journal_title：Lipids

authors： Kojima H,Inoue T,Sugita M,Itonori S,Ito M

更新日期：2010-07-01 00:00:00

abstract：:Mice exposed to cold rely upon brown adipose tissue (BAT)-mediated nonshivering thermogenesis to generate body heat using dietary glucose and lipids from the liver and white adipose tissue. In this report, we investigate how cold exposure affects the PI3 K/Akt signaling cascade and the expression of genes involved in ...

journal_title：Lipids

authors： Deiuliis JA,Liu LF,Belury MA,Rim JS,Shin S,Lee K

更新日期：2010-06-01 00:00:00

abstract：:The present study was performed to investigate the effect of dietary conjugated linoleic acid (CLA) on the growth performance, immune parameters and disease resistance to Aeromonas hydrophila of juvenile Jian carp. A total of 900 juvenile Jian carp (10.71 +/- 0.02 g) were randomly allocated into six groups of each thr...

journal_title：Lipids

authors： Jiang J,Zhao MJ,Lin F,Yang L,Zhou XQ

更新日期：2010-06-01 00:00:00

abstract：:The present study aimed to elucidate the effective phylogenetic specificity of distribution of a cis-4,7,10, trans-13-22:4 (22:4(n-9)Delta13trans) among pectinids. For this purpose, we extended the analysis of membrane glycerophospholipids FA composition to 13 species of scallops, covering 11 genera and 7 tribes repre...

journal_title：Lipids

authors： Kraffe E,Grall J,Palacios E,Guerra C,Soudant P,Marty Y

更新日期：2010-05-01 00:00:00

abstract：:Observational evidence suggests that in populations consuming low levels of n-3 highly unsaturated fatty acids, women have higher blood levels of docosahexaenoic acid (DHA; 22:3n-6) as compared with men. Increased conversion of alpha-linolenic acid (ALA; 18:3n-3) to DHA by females has been confirmed in fatty acid stab...

journal_title：Lipids

authors： Kitson AP,Stroud CK,Stark KD

更新日期：2010-03-01 00:00:00

abstract：:Bdellovibrionales is a phylogenetically diverse group of predatory prokaryotes, which consists of the two families Bdellovibrionaceae and Bacteriovoracaceae. We describe LPS and lipid A of the type strain Bacteriovorax stolpii DSM 12778, representing the first characterized endotoxin of a Bacteriovoracaceae member. It...

journal_title：Lipids

authors： Beck S,Müller FD,Strauch E,Brecker L,Linscheid MW

更新日期：2010-02-01 00:00:00

abstract：:Plasma phospholipid transfer protein (PLTP) mediates both net transfer and exchange of phospholipids between different lipoproteins. Animal studies have shown that it is closely related to the development of atherosclerosis. Although many studies have indicated that PLTP activity is increased in diabetes mellitus, the...

journal_title：Lipids

authors： Schlitt A,Schwaab B,Fingscheidt K,Lackner KJ,Heine GH,Vogt A,Buerke M,Maegdefessel L,Raaz U,Werdan K,Jiang XC

更新日期：2010-02-01 00:00:00

abstract：:Triacylglycerol (TAG) is the main storage lipid in plants. Acyl-CoA: diacylglycerol acyltransferase (DGAT1 and DGAT2) and phospholipid: diacylglycerol acyltransferase (PDAT) can catalyze TAG synthesis. It is unclear how these three independent genes are regulated in developing seeds, and particularly if they have spec...

journal_title：Lipids

authors： Li R,Yu K,Hildebrand DF

更新日期：2010-02-01 00:00:00

abstract：:Meal fatty acids have been shown to modulate the size and composition of triacylglycerol (TAG)-rich lipoproteins influencing the magnitude and duration of the postprandial plasma TAG response. As a result there is considerable interest in the origin of these meal fatty-acid induced differences in particle composition....

journal_title：Lipids

authors： Jackson KG,Bateman PA,Yaqoob P,Williams CM

更新日期：2009-12-01 00:00:00